our mission
Crystalys Therapeutics’ mission is to address the significant unmet medical needs of people living with gout. Guided by a focused commitment to scientific innovation and a passion for improving patient care, we develop targeted therapies to better control uric acid, reduce flares, resolve tophi and help prevent long-term joint damage.
With agility, diligence, and compassion, we strive to deliver meaningful, lasting improvements in patient outcomes.
about us
Crystalys Therapeutics is a clinical-stage biopharmaceutical company focused on advancing innovative therapies to address the significant unmet medical needs of patients living with gout.
Gout is a chronic metabolic disease driven by elevated levels of uric acid in the bloodstream. When uric acid accumulates, monosodium urate crystals can form and deposit in joints and tissues, leading to painful inflammatory flares and long-term joint damage. Despite the availability of currently approved treatments, many patients continue to struggle with inadequate uric acid control and ongoing disease burden and are in need of additional treatment options.
Crystalys is committed to developing therapies designed to improve uric acid management and help patients achieve and maintain healthy serum urate levels. The company’s lead investigational therapy, dotinurad, is a next-generation, highly selective urate transporter 1 (URAT1) inhibitor designed to reduce serum uric acid by targeting the renal transport pathways responsible for urate reabsorption.
Crystalys Therapeutics is headquartered in San Diego, California, and was co-founded by the Executive Team, Catalys Pacific, and Novo Holdings.
our values
: a strong feeling of enthusiasm or excitement for something or about doing
: a center of activity, attraction, or attention
: the power of moving quickly and easily; nimbleness
: steady, earnest, and energetic effort : devoted and painstaking work and application to accomplish an undertaking
: sympathetic consciousness of others’ distress together with a desire to alleviate it
management team
James Mackay, Ph.D.
President & Chief Executive Officer
Justin Thacker, CPA
Chief Financial Officer
Nihar Bhakta, M.D.
Chief Medical Officer
Ashwin Ram, M.D.
Chief Operating Officer
DeAnne Reid
Executive Director, Operations & Business Development
board of directors
BT Slingsby, M.D., Ph.D.
Catalys Pacific
Kenneth Harrison, Ph.D.
Novo Holdings
Rajeev Dadoo, Ph.D.
SR One
Chris Garabedian
Perceptive Advisors, Xontogeny
David Jin
Fortress Bio
James Mackay, Ph.D.
President & Chief Executive Officer
Tim Walbert
Independent Board Director